Naiyer A. Rizvi, MD, is aprofessor of medicine in the Department of Medicine and the director of Thoracic Oncology and Phase I Immunotherapeutics for the Division of Hematology and Oncology at Columbia University Medical Center. He also holds the Price Chair in Clinical Translational Research. Dr. Rizvi is an internationally recognized leader in the treatment of lung cancer and immunotherapy drug development. Prior to joining Columbia University Medical Center, his clinical research at Memorial Sloan Kettering Cancer played a significant role in the US Food and Drug Administration (FDA) approval path of a new class of immunotherapies, called immune checkpoint inhibitors for melanoma and lung cancer.
Dr. Rizvi’s research focus is studying mechanisms of sensitivity and resistance to immunotherapy. Through genetic testing of tumors, he has been able to improve the understanding of why immune checkpoint inhibitors work in certain patients. This work has been partially supported by Stand Up To Cancer -- Cancer Research Institute immunology funding. Also, in his research, he is studying why certain cancers do not respond to immune checkpoint inhibitors, so we can find better ways to harness the immune system to attack cancer cells. Dr. Rizvi oversees Phase 1 immunotherapy research in solid tumors at Columbia University Medical Center and is conducting key clinical studies of novel immunotherapy drugs and immunotherapy combinations to help more patients in the fight against cancer.