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Dr. David C. Metz is professor of medicine and associate chief for clinical affairs in the division of gastroenterology at Penn Medicine in Philadelphia, where he is director of the Acid-Peptic Disease Program and codirector of both the GI Physiology Laboratory and the Swallowing Disorders Program.

He is actively involved in clinical research, patient care, and teaching of students, residents, and fellows. Dr. Metz's clinical research program is particularly active in acid-peptic conditions including hypersecretory states such as Zollinger-Ellison syndrome, Helicobacter pylori infection, nonsteroidal anti-inflammatory drug gastropathy, and gastroesophageal reflux disease. He has been a principal investigator on a number of trials evaluating upper gastrointestinal disease states. He is also active in national gastroenterology societies and was a prior member of the Liason Committee for Recertification of the American Board of Internal Medicine (American Gastroenterological Association representative) and the US Food and Drug Administration Gastrointestinal Drugs Advisory Committee.

Dr. Metz earned his MBBCh (MD equivalent) from the University of the Witwatersrand in Johannesburg, South Africa. He moved to the United States in 1986 and pursued a residency in internal medicine at Albert Einstein Medical Center in Philadelphia. He completed a fellowship in gastroenterology in Washington, DC, in the combined Georgetown/Veterans Affairs Medical Center/National Institutes of Health (NIH) program. He remained on staff at the NIH for 2 more years as a senior staff fellow, performing basic research in pancreatic acinar cell secretion and clinical research in Zollinger-Ellison syndrome specifically.

In 1993, Dr. Metz moved to Philadelphia in the role of assistant professor in the clinician educator track at the University of Pennsylvania. He was promoted to associate professor in 1998 and full professor in 2003.