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Sugary Drinks Raise Risk of Premature Death in People with Type 2 Diabetes

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04/21/2023
news.harvard.edu

High consumption of sugar-sweetened beverages (SSBs) was associated with an elevated risk of premature death and incidence of cardiovascular disease among people with Type 2 diabetes, according to a new study led by researchers at Harvard T.H. Chan School of Public Health. Drinking beverages like coffee, tea, low-fat cow’s milk, and plain water was associated with lower risk of dying prematurely.

The study looked specifically at consumption of different beverages among patients with Type 2 diabetes. While many prior studies have linked beverage consumption and health outcomes such as cardiometabolic health, weight change, and mortality, those studies have primarily been among the general population.

“Beverages are an important component of our diet, and the quality can vary hugely,” said lead author Qi Sun, associate professor in the Departments of Nutrition and Epidemiology. “People living with diabetes may especially benefit from drinking healthy beverages — but data has been sparse. These findings help fill in that knowledge gap and may inform patients and their caregivers on diet and diabetes management.”

The study was published online Wednesday in The BMJ.

The researchers analyzed an average of 18.5 years of health data from 9,252 women participating in the Nurse’s Health Study and 3,519 men participating in the Health Professionals Follow-up Study, all of whom had been diagnosed with Type 2 diabetes at baseline or at some point during the study. Every two to four years, the participants reported on how often they consumed SSBs (including sodas, fruit punch, and lemonade), artificially sweetened beverages (ASBs), fruit juice, coffee, tea, low-fat cow’s milk, full-fat cow’s milk, and plain water.

The findings showed higher all-cause mortality, and higher incidence of and mortality from cardiovascular disease, among those who regularly consumed SSBs: Every additional daily serving of a SSB was associated with an 8 percent higher all-cause mortality. Inversely, all-cause mortality and incidence of and mortality from cardiovascular disease decreased among those who regularly consumed healthier beverages such as coffee, tea, low-fat cow’s milk, and/or plain water.

Replacing one daily serving of a SSB with one serving of coffee was associated with an 18 percent lower risk of all-cause mortality and a 20 percent  lower risk of cardiovascular disease mortality; tea with 16 percent and 24 percent lower risk; plain water with a 16 percent and 20 percent lower risk; and low-fat cow’s milk with a 12 percent  and 19 percent lower risk. Drinking ASBs was also associated with healthier outcomes, but less so: Replacing one daily serving of a SSB with an ASB was associated with an 8 percent lower risk of all-cause mortality and a 15 percent lower risk in cardiovascular disease mortality.

“People living with diabetes should be picky about how they keep themselves hydrated,” said Sun. “Switching from sugar-sweetened beverages to healthier beverages will bring health benefits.”

Other Harvard Chan School co-authors included Le Ma, Yang Hu, Derrick Alperet, Vasanti Malik, JoAnn Manson, Eric Rimm, and Frank Hu.

Funding for the study came from the National Institutes of Health grants UM1 CA186107, U01 CA167552, R01 HL034594, R01 HL035464, DK126698, DK120870, and DK119268.

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Schedule23 Feb 2024