| NCT07073430 | Development and Demonstration of a Precision Prevention and Treatment System for Colorectal Tubular Adenomas Lesions | gastroenterology | medical ai diagnostics | RECRUITING | n/a | Renmin Hospital of Wuhan University | 4000 | The accuracy rate of diagnosing adenomas |
| NCT06676059 | SMART-r: Substance Monitoring and Active Relapse Tracking Repository | psychiatry | digital therapeutics | RECRUITING | n/a | National Institute on Drug Abuse (NIDA) | 10000 | SMARTr data repository |
| NCT07837336 | An Evaluation of Nutritional Status, Body Composition, and Dietary Intakes of Filipino Pediatric Patients With Inborn Errors of Intermediary Protein Metabolism | pediatrics | digital therapeutics | RECRUITING | n/a | Food and Nutrition Research Institute, Philippines | 176 | Weight (in kilograms) and age (in years and months) will be combined to report Weight-for-Age in Z-score |
| NCT03910465 | Children and Adults With Chordoma | oncology | medical ai diagnostics | RECRUITING | n/a | National Cancer Institute (NCI) | 300 | To characterize the natural history of chordoma, including clinical presentation and patterns of disease progression |
| NCT00040352 | Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma | oncology | medical ai diagnostics | RECRUITING | n/a | National Cancer Institute (NCI) | 3000 | All cancers that occur in individuals and families at high risk of melanoma |
| NCT07582016 | Partnership to Reduce Obesity in Community Health Center Patients (SMARTLife Utah) | endocrinology | digital therapeutics | RECRUITING | n/a | University of Utah | 5354 | Reach-Enroll |
| NCT07714980 | TEAS Timing for Gastrectomy Recovery (TEAS-TIME Trial) | oncology, surgery | medical ai diagnostics | RECRUITING | n/a | The Affiliated Hospital of Qingdao University | 300 | Time to First Flatus After Surgery |
| NCT05730283 | Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin | neurology | digital therapeutics | RECRUITING | Phase 2 | Kevin Winthrop | 105 | Mitigation or Prevention of Ototoxicity |
| NCT07675889 | Intraoperative Longitude-Latitude-Depth Localization Versus Preoperative CT-Guided Percutaneous Lung Puncture Localization for 0.8-2 cm Peripheral Pulmonary Nodules | pulmonology, surgery | medical ai diagnostics | RECRUITING | n/a | Qilu Hospital of Shandong University | 274 | Localization Accuracy Rate |
| NCT06906640 | Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2) | endocrinology | digital therapeutics | RECRUITING | n/a | Duke University | 212 | CKD GDMT Opportunity Score at 6 months |
| NCT04798131 | fMRI-based Neurofeedback to Relieve Drug-resistant Auditory Hallucinations | psychiatry | medical ai diagnostics | RECRUITING | n/a | University Hospital, Lille | 84 | Change from baseline in the Auditory Hallucination Rating Scale (AHRS) measure of hallucinations severity |
| NCT05936619 | MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System | neurology | medical ai diagnostics | RECRUITING | n/a | Nader Pouratian | 2 | Continuous trajectory decoding |
| NCT06719206 | Reduce Sedentary Behavior During Cancer Treatment - the RedSedCan Study | oncology | digital therapeutics | RECRUITING | n/a | Mälardalen University | 210 | Sedentary behavior time |
| NCT07312942 | Effects of Controlled Breathing Added to Therapeutic Exercise in Multiple Myeloma | oncology | digital therapeutics | RECRUITING | n/a | Universidad Complutense de Madrid | 32 | Somatic Symptom Questionnaire |
| NCT07150832 | Efficacy of the I-CARE Digital Health Intervention | psychiatry | digital therapeutics | RECRUITING | n/a | Dartmouth-Hitchcock Medical Center | 173 | Depression Anxiety Stress Scales Youth Version (DASS-Y ) |
| NCT06000787 | MCT for the Harvard/UCSF ROBIN Center | oncology | medical ai diagnostics | RECRUITING | n/a | Brigham and Women's Hospital | 47 | Event-free survival by tumor heterogeneity |
| NCT05704920 | Integrating Artificial Intelligence Into Lung Cancer Screening. | oncology | medical ai diagnostics | RECRUITING | n/a | Centre Hospitalier Universitaire de Nice | 2722 | Diagnosis of lung disease |
| NCT07852156 | Cooling During Inpatient Rehabilitation in Persons With MS | neurology | medical ai diagnostics, digital therapeutics | RECRUITING | n/a | Klinik Valens | 42 | State Fatigue |
| NCT06749366 | Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing | oncology | medical ai diagnostics | RECRUITING | n/a | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 100 | Comprehensively define the phenotypic features of patients with OD and MS. |
| NCT07851480 | Validation of an Algorithm for Predicting Awakenings Associated With Trauma-related Nightmares, Based on the Analysis of Physiological Patterns in Military and Former Military Patients Suffering From Post-traumatic Stress Disorder | psychiatry | medical ai diagnostics, wearables | RECRUITING | n/a | Direction Centrale du Service de Santé des Armées | 27 | Sensitivity of the CAUD-PIN algorithm in predicting Trauma-related nightmare awakenings |
| NCT05675410 | A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab | oncology, surgery | medical ai diagnostics | RECRUITING | Phase 3 | National Cancer Institute (NCI) | 1875 | Progression-free survival (PFS) in rapid early responder (RER) patients |
| NCT07852650 | Digital STEADI Efficacy | psychiatry | medical ai diagnostics, digital therapeutics | RECRUITING | Phase 1/Phase 2 | Friendi.fi Corporation | 300 | Change from baseline fear of falling as measured by the Fall Efficacy Scale International (FES-I) |
| NCT04957095 | Motor Network Physiology | neurology | medical ai diagnostics | RECRUITING | n/a | University of Texas Southwestern Medical Center | 120 | cortical ECoG and subcortical recordings |
| NCT07852403 | PAH-SDB: Sleep-Disordered Breathing and Outcomes in Pulmonary Arterial Hypertension | cardiology | medical ai diagnostics, digital therapeutics, wearables | RECRUITING | n/a | Chinese Pulmonary Vascular Disease Research Group | 1500 | Prevalence and phenotypic distribution of sleep-disordered breathing and nocturnal hypoxemia |
| NCT02504879 | Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease | rheumatology | medical ai diagnostics | RECRUITING | n/a | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 350 | Disease progression |
| NCT04877977 | Long-term Observation of Participants With Mood Disorders | psychiatry | medical ai diagnostics | RECRUITING | n/a | National Institute of Mental Health (NIMH) | 1000 | Score on Beck Depression Inventory (suicide item removed) |
| NCT07572136 | Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL) | oncology | medical ai diagnostics | RECRUITING | Phase 1 | National Cancer Institute (NCI) | 57 | To assess the safety of administering escalating doses of TSLPR-CART containing a tEGFR suicide switch to determine an MTD |
| NCT06660225 | Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder | psychiatry | medical ai diagnostics | RECRUITING | n/a | Nader Pouratian | 10 | Efficacy of amSTN stimulation on OCD symptoms as measured by YBOCS |
| NCT07706244 | Preoperative Anxiety and One-year Patient-reported Outcomes in Orthopedic Surgery Patients Receiving Enhanced Recovery After Surgery or Conventional Care | psychiatry, surgery | medical ai diagnostics | RECRUITING | n/a | Buddhist Tzu Chi General Hospital | 220 | Preoperative Anxiety (APAIS Score) |
| NCT07005648 | Brazilian Registry of Menopausal Health | womens health | digital therapeutics | RECRUITING | n/a | Science Valley Research Institute | 1592 | Proportion of participants aged 35 to 65 classified as being in the menopausal transition or postmenopause. |
| NCT06954597 | Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis | dermatology | digital therapeutics | RECRUITING | Phase 2 | Topadur Pharma AG | 15 | Local treatment emergent adverse events (TEAEs) |
| NCT04986605 | Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis | dermatology | digital therapeutics | RECRUITING | Phase 2 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 15 | Change in skin thickness measured by modified Rodnan Skin Score |
| NCT07852338 | a Prospective, Multicenter, Randomized Controlled Trial, With a Non-randomized Sentinel Cohort, Evaluating the Efficacy of Bioxheal, a Single-layer Placental-derived Biologic in Nonhealing Diabetic Foot Ulcers | endocrinology | digital therapeutics | RECRUITING | Phase 3 | Applied Biologics, LLC | 253 | Primary Endpoint - Proportion of Target Ulcers with Complete Closure at Week 12 |
| NCT07486934 | Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1 | neurology | digital therapeutics, wearables | RECRUITING | Phase 3 | Dyne Therapeutics | 150 | 5 Times Sit-To-Stand (5×STS) Time |
| NCT07695389 | Efficacy of a Novel Cellular, Acellular, Matrix-like Product (CAMP) Plus Standard of Care Versus Standard of Care Alone in the Management of Post-Mohs Micrographic Surgery Defects. | dermatology, surgery | digital therapeutics | RECRUITING | n/a | BioLab Holdings | 160 | Complete Wound Closure |
| NCT07667478 | NON-INVASIVE BRAIN STIMULATION FOR MEMORY LOSS IN EARLY ALZHEIMER'S DISEASE | neurology | digital therapeutics | RECRUITING | n/a | Chi-Ying (Roy) Lin | 40 | MMSE |
| NCT06860607 | Environment and Alcohol: A Pilot Study | psychiatry | digital therapeutics | RECRUITING | Phase 1 | National Institute on Drug Abuse (NIDA) | 44 | Evaluate the effects of EE on alcohol consumption |
| NCT06437132 | Decoding Death and Dying in People With Dementia by Digital Thanotyping | neurology | digital therapeutics, wearables | ENROLLING_BY_INVITATION | n/a | University of Bergen | 270 | Edmonton Symptom Assessment System (ESAS++) |
| NCT06908083 | Immunologic and Virologic Parameters During Analytical Treatment Interruption Following Combination bNAb Therapy During Suppressive ART | infectious disease | digital therapeutics | ENROLLING_BY_INVITATION | Phase 1 | National Institute of Allergy and Infectious Diseases (NIAID) | 50 | Time to Restart ART |
| NCT07376733 | Effects of Controlled Breathing on Cardiorespiratory Variables in Multiple Myeloma | oncology | digital therapeutics | RECRUITING | n/a | Universidad Complutense de Madrid | 26 | HRV SDNN pre-postintervention |
| NCT07753460 | Low-Level Laser Therapy in the Treatment of Trigger Finger | sports medicine | digital therapeutics | RECRUITING | n/a | Dokuz Eylul University | 91 | Visual Analog Scale |
| NCT07673328 | Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal | rheumatology, surgery | surgical robotics | RECRUITING | n/a | University of Michigan | 65 | Muscle effort |
| NCT06883097 | Quitting Matters Human Immunodeficiency Virus Hybrid Trial | psychiatry | digital therapeutics | RECRUITING | n/a | Wake Forest University Health Sciences | 314 | Biochemically verified 7-day point prevalence abstinence at 6, 12, 18, and 24-weeks |
| NCT06043440 | Down Syndrome Obstructive Sleep Apnea | pulmonology | digital therapeutics | RECRUITING | Phase 2 | Brigham and Women's Hospital | 230 | Behavior Rating Inventory of Executive Function 2 (BRIEF2) working memory score |
| NCT07848815 | Risk-Based Lung Cancer Detection in COPD Patients | oncology | medical ai diagnostics | RECRUITING | n/a | Vejle Hospital | 1000 | Number of histopathologically confirmed lung cancers |
| NCT05818384 | Wakaya: Rising Up for Choctaw Youth Health | psychiatry | digital therapeutics | RECRUITING | n/a | University of Washington | 176 | Change in physical activity assessed by self-report |
| NCT07299019 | A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis | neurology | digital therapeutics | RECRUITING | Phase 3 | Zenas BioPharma (USA), LLC | 990 | Time to onset of confirmed disability progression (CDP) events, confirmed over at least 24 weeks |
| NCT07497087 | A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis | dermatology | digital therapeutics | RECRUITING | Phase 3 | Boehringer Ingelheim | 448 | Time to the first occurrence of disease progression or all-cause death |
| NCT07446192 | Magnetoencephalography (MEG) Pilot Study | neurology | wearables | RECRUITING | n/a | University of Florida | 10 | Change in brain electrical activity measured by magnetoencephalography (MEG) before and after treatment with focused ultrasound |
| NCT05558605 | Use of Artificial Intelligence-Guided Echocardiography to assIst cardiovascuLar Patient managEment | cardiology | medical ai diagnostics | RECRUITING | n/a | Baker Heart and Diabetes Institute | 612 | Diagnosis of cardiac dysfunction or heart valve disease |
| NCT05739331 | Augmented Endobronchial Ultrasound (EBUS-TBNA) With Artificial Intelligence | oncology | medical ai diagnostics | RECRUITING | n/a | Norwegian University of Science and Technology | 50 | Capability |
| NCT07849608 | Silent Evaluation of DeepTRG for Assessing Tumor Response After Preoperative Treatment in Stomach and Gastroesophageal Junction Cancer | oncology | medical ai diagnostics, digital therapeutics | RECRUITING | n/a | Qun Zhao | 200 | Patient-Level Complete Automated Assessment Rate |
| NCT06376968 | Prospective, Multicentre, Randomized, Controlled, Cross-over Study on the Safety and Performance of the Biologic Fusion Option of DialogiQ Compared to Haemodialysis Without Biologic Fusion in Hypotension Prone Patients on Maintenance Haemodialysis | nephrology | medical ai diagnostics | RECRUITING | n/a | B.Braun Avitum AG | 56 | Post-dialysis body weight |
| NCT06160128 | Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA) | infectious disease | medical ai diagnostics | RECRUITING | n/a | VA Office of Research and Development | 400000 | Receipt of any COVID-19 pharmacotherapy, including sotrovimab, nirmatrelvir boosted with ritonavir, molnupiravir, or remdesivir |
| NCT07693049 | Cardiopulmonary Exercise Testing-based High-intensity Interval Training For Improving Heart Failure With Preserved Ejection Fraction | cardiology | digital therapeutics | RECRUITING | n/a | Peking University Third Hospital | 192 | Peak VO2 |
| NCT06732596 | Sustaining Recovery for People on Opioid Agonist Treatment With Conversational Agents | psychiatry | digital therapeutics | RECRUITING | n/a | Boston Medical Center | 100 | Number of participants that stay engaged in buprenorphine treatment |
| NCT07497334 | A Novel Multi-Modal Approach to Promote Functional Outcomes in Cognitively Frail Older Adults | psychiatry | digital therapeutics | RECRUITING | n/a | The Hong Kong Polytechnic University | 45 | Montreal Cognitive Assessment |
| NCT06328361 | Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer | oncology, surgery | digital therapeutics | RECRUITING | n/a | Tampere University Hospital | 200 | Disease-free survival |
| NCT07848841 | Online Perioperative Education Program on Patient Satisfaction and Clinical Outcomes for Head and Neck Surgery | oncology, surgery | digital therapeutics | RECRUITING | n/a | Washington University School of Medicine | 50 | Change in ORTC QLQ-INFO25 Satisfaction Score |
| NCT07848594 | The Impact of Overnight Active Temperature Regulation on Gut Microbiome, Inflammation, and Circadian Rhythm. | psychiatry | digital therapeutics | RECRUITING | n/a | Eight Sleep Inc. | 100 | Gut Microbiome Composition |
| NCT06515249 | Integrative Therapies in Multiple Myeloma | oncology | digital therapeutics | RECRUITING | n/a | Bnai Zion Medical Center | 300 | Quality-of-life specific to myeloma patients |
| NCT07480590 | GLOW: Gender-Affirming Care and Mental Health: A Longitudinal Study On Quality of Life, Work Life, and Healthcare Outcomes | psychiatry | digital therapeutics | RECRUITING | n/a | Region Skane | 500 | Change in Quality of Life |
| NCT07609108 | Pridopidine Phase 3 Study in Huntington's Disease | psychiatry | digital therapeutics | RECRUITING | Phase 3 | Prilenia | 400 | Change in Composite Unified Huntington's Disease Rating Scale (cUHDRS) |
| NCT05991713 | Geolocation Positional System (GPS) Experience | psychiatry | digital therapeutics | RECRUITING | n/a | University of Miami | 100 | Change in positive emotional response as measured by ecological momentary assessment |
| NCT05836987 | The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation | cardiology | digital therapeutics | RECRUITING | Phase 3 | Johns Hopkins University | 5350 | To assess whether AFSW-guided, time-delimited DOAC therapy is non-inferior to continuous DOAC therapy for a composite endpoint that includes: (1) Ischemic stroke; (2) Systemic embolism; (3) All-cause mortality. |
| NCT06826014 | TREC@TAMU Cancer Prevention Registry and Repository | oncology | digital therapeutics | RECRUITING | n/a | Texas A&M University | 2500 | Frequency and nature of ADRs on the Naranjo Scale Questionnaire |
| NCT07296874 | Acute Effects of Cannabis on Cognition and Affect | psychiatry | digital therapeutics, wearables | RECRUITING | Phase 2 | Washington State University | 92 | Event-Based Prospective Memory - Number of Difficulty Ratings Provided |
| NCT06616363 | Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities? | cardiology | digital therapeutics, wearables | RECRUITING | n/a | Virginia Commonwealth University | 120 | Functional Disability Inventory (FDI) |
| NCT07823608 | A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1) | pulmonology | medical ai diagnostics | RECRUITING | Phase 3 | Pfizer | 258 | Change From Baseline in Apnea-Hypopnea Index (AHI) |
| NCT06631729 | Targeting Transdiagnostic Self-regulatory Factors and Eating Disorder Pathology Among Adults With BInge-spectrum Eating disOrders: A mHEALTH Interoceptive Exposure Intervention (the Bio-HEALTH Study) | psychiatry | digital therapeutics | RECRUITING | n/a | University of Minnesota | 80 | Momentary binge eating |
| NCT07096973 | Cardiac REhabilitation COhort at the Medicine Campus DaVos to invEstigate Recovery | cardiology, surgery | digital therapeutics | RECRUITING | n/a | Hochgebirgsklinik Davos | 10000 | Composite of cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke, and hospitalization for heart failure |
| NCT07847918 | A Fully Remote Feasibility Trial of Phenylbutyrate for SLC6A1-Related Disorders | neurology | digital therapeutics, wearables | RECRUITING | Phase 2 | Scripps Translational Science Institute | 20 | Recruitment efficiency |
| NCT04869059 | Treating Mild Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation | neurology | digital therapeutics | RECRUITING | n/a | The University of Texas at Dallas | 136 | Treatment group differences in change from Baseline to 3-months Post-Treatment on the Controlled Oral Word Association Test |
| NCT07846345 | Case Management for Microtia | pediatrics | digital therapeutics | RECRUITING | n/a | Jing Xu | 188 | Incidence of postoperative complications after ear reconstruction |
| NCT07688720 | Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause | psychiatry | wearables | RECRUITING | n/a | Texas Christian University | 20 | Daily Record of Severity of Problems (DRSP) |
| NCT07847424 | Heat Therapy During Reduced Physical Activity | psychiatry | wearables | RECRUITING | n/a | Brigham Young University | 60 | Femoral artery endothelial function |
| NCT07690163 | DIabetes GLycemic Assessment in Newly Confirmed Episodes | endocrinology | wearables | RECRUITING | n/a | Nazarii Kobyliak | 80 | Changes in HbA1c level |
| NCT05909046 | A Randomized Controlled Trial of Diabetes Screening Immediately Postpartum (DIP) and Follow Up PP CARE | endocrinology | wearables | RECRUITING | n/a | Ohio State University | 104 | Rate of postpartum diabetes mellitus screening |
| NCT06605664 | Hyperpolarized 13C-MRI in Patients With Hepatocellular Carcinoma Undergoing Radiotherapy, Atezolizumab, and Bevacizumab | oncology | medical ai diagnostics | RECRUITING | Phase 2 | Chang Gung Memorial Hospital | 45 | Dynamic Nuclear Polarization (DNP) |
| NCT07845929 | Clinical Application of a Low-Dose CBCT AI Model | neurology | medical ai diagnostics | RECRUITING | n/a | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 1380 | Radiation dose |
| NCT07761546 | AIM-TEST: Microbiome-Targeted Nutrition for Functional Secondary Hypogonadism | urology | medical ai diagnostics | ENROLLING_BY_INVITATION | n/a | Varol TUNALI | 112 | Mean Change From Baseline in Mean Fasting Morning Serum Total Testosterone at Week 12 |
| NCT07736547 | AIM-WEIGHT: AI-Guided Microbiome-Targeted Nutritional Intervention for Weight Loss | endocrinology | medical ai diagnostics, digital therapeutics | ENROLLING_BY_INVITATION | n/a | Varol TUNALI | 80 | Percent Change in Body Weight From Baseline to Week 12 |
| NCT07019714 | Daoyin Technique for Improving Exercise Endurance in IPF | pulmonology | digital therapeutics | RECRUITING | n/a | Affiliated Hospital of Liaoning University of Traditional Chinese Medicine | 236 | 6 Six Minute Walk Distance(6MWD) |
| NCT05390827 | Remote Digital Physiologic Data Collection in Cancer: An MSK Registry Protocol | oncology | digital therapeutics | RECRUITING | n/a | Memorial Sloan Kettering Cancer Center | 3692 | establish a mechanism within the institution to prospectively collect / extract digital remote physiological data among patients with cancer |
| NCT04162938 | Use of a Patient-Centered Electronic App to Increase ED Patient's Knowledge on HCV to Improve the HCV Care Continuum | gastroenterology | digital therapeutics | RECRUITING | n/a | Johns Hopkins University | 308 | Linkage to care rate (days) |
| NCT06879184 | Cohort of the Specialist Network Infectious Diseases | infectious disease | digital therapeutics | RECRUITING | n/a | Goethe University | 15000 | Provision of clinical patient data and biosamples from highly relevant entities of infectious diseases for scientific projects, with no predefined specific outcome, but potentially applicable to various research objectives |
| NCT05703412 | Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness | psychiatry | digital therapeutics, wearables | ENROLLING_BY_INVITATION | n/a | Butler Hospital | 180 | Brief Psychiatric Rating Scale (BPRS) |
| NCT05785065 | Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease | pulmonology | digital therapeutics | RECRUITING | Phase 2 | Centre hospitalier de l'Université de Montréal (CHUM) | 35 | Total number of potentially eligible patients identified per site |
| NCT07216690 | Pregnenolone as a Treatment for Cannabis Intoxication | psychiatry | digital therapeutics | RECRUITING | Phase 2 | Johns Hopkins University | 20 | Mean Peak Change From Baseline Drug Effect as Assessed by the Drug Effect Questionnaire (DEQ) |
| NCT07426926 | Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures | emergency medicine, surgery | digital therapeutics | RECRUITING | n/a | University of Nove de Julho | 42 | Quick-DASH functional scale - 2 weeks |
| NCT06876246 | SBIR/ STTR Family Check-up Online | psychiatry | digital therapeutics | RECRUITING | n/a | University of Oregon | 670 | Change from Baseline in Child Depression (Parent report) |
| NCT06724406 | FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing) | endocrinology | digital therapeutics, wearables | RECRUITING | n/a | University of North Carolina, Chapel Hill | 256 | Change in Body weight |
| NCT06206226 | The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study | psychiatry | digital therapeutics | RECRUITING | n/a | University of Wisconsin, Madison | 8 | Change in Personal Health Questionnaire Depression Scale score |
| NCT07013578 | TIDHI Mental Health in IBD Patients Study | gastroenterology | digital therapeutics | RECRUITING | n/a | TIDHI Innovation Inc. | 100 | Change in Generalized Anxiety Disorder 7-item Scale (GAD-7) Score |
| NCT07599072 | PREdiabetes GLycemic Impact and Data Evaluation | endocrinology | wearables | RECRUITING | n/a | Nazarii Kobyliak | 80 | Changes in HbA1c level |
| NCT07491952 | Continuous Dual Aspiration Technique With Zoom System for Stroke | neurology | wearables | RECRUITING | n/a | Imperative Care, Inc. | 750 | Proportion of patients achieving modified Thrombolysis in Cerebral Infarction (mTICI) score of ≥2c at the end of procedure, as adjudicated by independent core-lab |
| NCT07281261 | tAN for Substance Use Disorder | psychiatry | wearables | RECRUITING | n/a | Spark Biomedical, Inc. | 20 | Clinical Institute Withdrawal Assessment of Alcohol Scale, Revised (CIWA-Ar) |
| NCT06157840 | Development of an mHealth Behavioral Sleep Medicine Intervention for Use During Medication Assisted Treatment for MOUD | psychiatry | digital therapeutics | RECRUITING | n/a | Medical University of South Carolina | 40 | Enrollment feasibility/acceptability benchmark of at least 30 persons completing entire study period - Enrollment and retention percentages |
| NCT07316517 | Versius Clinical Study in Robot Assisted Inguinal Hernia Repair Surgery | surgery | surgical robotics | RECRUITING | n/a | CMR Surgical Ltd | 30 | Success rate |
| NCT07033169 | A Skin Image Reference Tool to Aid Healthcare Providers' Diagnosis | dermatology | medical ai diagnostics | RECRUITING | n/a | Wake Forest University Health Sciences | 400 | concordance of Belle.ai diagnoses with physician diagnoses. |