Factor XIa Learning Center
The Evolving Role of Anticoagulation in Acute Coronary Syndromes, Atrial Fibrillation, Secondary Stroke Prevention

Your Clinician-Focused Hub for Factor XIa Pathway Inhibition
Through expert interviews, interactive case discussions, multidisciplinary panels, and patient perspectives, leading authorities in thrombosis, cardiology, neurology, and hematology explore the rapidly evolving landscape of Factor XIa inhibition. Gain access to the latest scientific insights and clinical trial evidence shaping a new era of anticoagulation—one aimed at maintaining protection against thrombotic events while minimizing bleeding risk. Empower clinicians with practical strategies to individualize antithrombotic care, optimize safety and efficacy in high-risk populations, and translate emerging evidence into confident, real-world application.
Educational Activities
CME programs exploring Factor XIa pathway inhibition in acute coronary syndromes, secondary stroke prevention, and atrial fibrillation.
Key Statistics
Understanding the scope and impact of thrombotic and bleeding complications.
Every year, 1 in 4 people worldwide die from conditions related to thrombosis
People in the U.S. are hospitalized with acute coronary syndromes yearly, with recurrence rates of 4.4-6.7%
Americans are estimated to be affected by atrial fibrillation, with untreated patients 5x more likely to have a stroke than those without
795,000 stroke events occur yearly in America, with the risk of recurrent stroke in someone who has already had one is 6-15x higher than the risk in the general population
Amongst DOAC users' risk of ICH is 0.07-0.5%, which becomes impactful at scale in aging populations
Key Takeaway
Bleeding is a significant problem and we need solutions that address this across Atrial Fibrillation, Acute Coronary Syndromes, and Secondary Stroke Prevention.
Expert Faculty & Steering Committee
Our distinguished expert faculty brings together leading authorities in cardiology, thrombosis research, stroke prevention, and clinical trials from premier institutions worldwide.

Valeria Caso

C. Michael Gibson

Robert A. Harrington

S. Claiborne Johnston

Carolyn S. P. Lam

Roxana Mehran

Manesh R. Patel

Tatjana Potpara

Christian T. Ruff

Mukul Sharma

Ashkan Shoamanesh

Jeffrey I. Weitz
Resource Center
Clinical practice guidelines for acute coronary syndromes, secondary stroke prevention, and atrial fibrillation management.

